Molecular basis of inherited diseases in companion animals; developing polymorphic markers for the canine Y chromosomes to understand the relationship between different dog breeds.
Pigmentation biology; hereditary ocular disorders; equine genomics and genetics.
Fertilization and fertility; sperm-oocyte membrane protein interactions, species variation and the effect of toxicants.
My research focus is on the husbandry, behavior, and welfare of small to large scale poultry production. I am particularly interested in understanding the challenges facing small scale and backyard poultry flocks as well as the impacts of housing systems on poultry health and welfare on large scale facilities. I am also interested in developing on farm assessment tools for producers to monitor the health and welfare of their own flocks.
Development of statistical methods and computational algorithms for quantitative and statistical genetics, including genomic prediction and genome-wide association studies. Development of software tools for whole-genome analyses. Statistical models for –omic data.
Biochemistry of sex steroid synthesis, conceptus development, sexual differentiation, comparative reproduction and adrenal function.
Aquatic toxicology and water quality; molecular mechanisms of toxicology.
Avian developmental genetics, embryology, cytogenetics, and genomics.
Reproductive and developmental biology. Paracrine and endocrine regulation of follicle and oocyte development and carry over effects of adverse environments during folliculogenesis on embryonic development. Biology of ovarian oocyte progenitor cells (oogonial stem cells) and their potential to improve and restore female fertility. application of basic concepts of reproductive biology and assisted reproductive techniques to improve animal and human health and efficiency of agriculture worldwide.
Ruminant nutrition of dairy cattle; mammary gland synthesis of milk protein and fat; nutrient digestion, absorption, and metabolism; evaluation of by-product feedstuffs and forage quality.
Quantitative applications; biological and production systems modeling; feed and fiber evaluations.
Physiological ecology of aquatic species, primarily fishes.
Companion animal nutrition: trace mineral and amino acid metabolism, feline and canine nutrient requirements, obesity, improvement of pet foods, the role of clinical nutrition in the management and prevention of disease.
Equine genetics, vitamin-E associated neurodegeneration
Disease ecology, small mammal conservation and disease, disease persistence in ecologically complex communities, tick-borne disease
Avian diseases, production and management, preventive measures to improve flock health, preventive veterinary medicine, vaccine design, molecular virology, food safety, commercial poultry improvement and international poultry development programs.
The driving force in my current research program is to be at the forefront of environmental and production sustainability and ecological integrity. To achieve this vision my research is focused into three distinct, yet overlapping applied research themes; (1) Aquaculture, (2) Invasion Biology and (3) Environmental/Ecological Toxicology. This research usually addresses data gaps and provides scientific solutions, determined through rigorous experimentation, meeting the immediate biological and engineering needs of the aquaculture industry and natural resource community.
Systems microbiology, microbial proceses in natural and artificial ecosystems, microbes and microbial enzymes for agricultural, medical, and industrial applications, microbe-host interaction, gastrointestinal microbiology, biofuels, bioproducts, bioremediation, microbial dark matter.
Research Interests: Ontogeny and heritability of stress-coping styles in domestic farm animals; cognitive evaluation of affective states in animals.
Endocrine regulation of mammary gland development, lactation and breast cancer, gene expression and cell-cell interactions.
Ruminant nutrition and physiology; pediatric nutrition using neonatal pig model.
Kinetic and Kinematic analysis in Dogs; Evidenced based research, Biomechanics
Modeling sustainable agricultural production. Energy and nutrient requirements of cattle, swine, and poultry. Empirical, mechanistic, and simulation models of nutrient utilization. Modeling of nutrient dynamics in manure; and greenhouse gas emissions of animals, manure and soil.
Retardation of lipid oxidation in poultry muscle, eggs and their products is the primary focus of my research. A series of antioxidants have been used, including polyphosphates and tocopherols, especially vitamin E. Presently, investigations center on the use of hydroxytyrosol, a by-product from olive oil processing, and α-tocopherol from tomato pomace, an agricultural by-product consisting of peels, cores, seeds, stems and green tomatoes from tomato processing.
Cellular osmoregulation, intracellular stress signaling, comparative genomics and proteomics of environmental adaptation in fish and mammals.
Mainly focused on clinical nutrition of dogs and cats, nutrient bioavailability, and amino acid nutrition
Feed ingredient evaluation for pigs and/or poultry; Dietary strategies on prevention and control of pig diseases; Swine nutrition on gut health and immunology; alternatives to in-feed antibiotics.
Use of transgenic livestock to fight diarrheal illnesses; microbiota modulation and resistance to disease; translational research using the pig as an animal model; goat casein genotypes and milk functionality.
My research program focuses on interplay between the behavior, welfare and management of poultry, including ducks, turkeys, laying hens and broilers; development of strategies to help minimize behavior-related poultry management issues while optimizing bird welfare and productions
Applied ethiology, behavioral management, animal well-being, wildlife conservation, behavioral ecology.
Improving equine management, behavior and welfare with a specific interest in donkeys, mules, hinnies and working equids in developing countries.
Animal Genomics; molecular genetics; animal growth; milk composition.
Animal waste management.
Reproduction, male reproduction, sperm cell biology, gamete cyropreservation biology, spermatogonial stem cells and transplantation.
Physiology; musculoskeletal biology; development, maturation, and repair; extracellular matrix/niche organization; tissue engineering; functional genomics; mouse model; equine; livestock
Animal genetics and genomics; conservation and ecological genetics and genomics; genomics and bioinformatics technology development; salmonid fishes.
Air quality research related to livestock production, especially quantification of ammonia, dust, and odor emissions in dairies, beef feedlots, and poultry operations. Environmental physiology research, focusing on effects of air emissions on animal health and welfare.
Transgenic animals; growth and differentiation, molecular genetics; cytogenetics, equine genetics.
Cell and molecular biology, animal growth and development of genetic markers.
Computer decision support software; beef quality assurance; standardized performance analysis for cattle and sheep ranches. Animal management systems; resource use in animal agriculture; beef cattle growth.
Food Animal Herd Health & Reproduction; Epidemiology; Antimicrobial Resistance.
Effectiveness of teaching methodologies and technologies as they apply to animal science courses; pedagogically sound approaches to curriculum and course development for traditional and non-traditional animal science students; applied livestock nutrition focusing on use of alternative feed ingredients.
Dairy herd health management including hypocalcemia, lameness, judicious use of antibiotics, and feeding and silage management
Protein and amino acid nutrition of dairy cows; evaluation and development of methods to predict forage energy content; nutritional strategies to reduce the environmental impact of dairy cows; development and evaluation of predictive whole cow biological models.
Epigenetic mechanisms controlling early embryonic development and pluripotency. Improving methodologies for animal cloning by nuclear transplantation and in vitro embryo production. Embryonic stem cell (ESC) biology and induction of pluripotency by defined factors (iPSC).
Modeling of nutrition and health in beef and dairy cattle, systems analysis of feed management and waste.
Neuroendocrine regulation of feeding behavior, body weight and glucose control; Mechanisms linking psychological stress and metabolic disease
Ecology, conservation, and genetics of wild carnivores.
Our laboratory focuses on ruminant livestock production, across geographic locations and levels of biological organization. Projects range from examination of interactions among nutrition, genetics and physiological state, all the way to regional studies of environmental impacts of different production systems. Recently, a major emphasis has been on understanding the genetic and physiological mechanisms underlying variations in feed efficiency in beef cattle. This work requires in vivo experiments in conjunction with in silico modeling analyses. Mathematical modeling is used at all levels of biological and enterprise organization to identify critical areas of research, design appropriate experiments, and aid in interpretation of results.
Skeletal injuries in equine athletes, silicate associated osteoporosis in horses, musculoskeletal biomechanics.
Director of Aquatic Health Program and State certified Aquatic Toxicology Laboratory. The Director conducts aquatic, embryonic, and developmental toxicology and endocrine disruption on invertebrate, fish and shellfish using biochemical, molecular, nutritional, and histopathological biomarkers.
Conservation biology of wild vertebrates, primarily reptiles and amphibians.
Ecological Physiology; Integrative Stress Biology; Environmental Genomics; Climate Change Biology.
Study of genetic markers in domestic animals. Equine genomics; development of a genome-scan microsattellite panel for linkage analysis and chromosomal location of traits of interest.
Animal welfare, animal behavior, effect of environmental conditions (housing, weather) and management decisions.
Transgenic modification of biochemical pathways to improve the quality of animal products for consumers; application of biotechnology to solve applied problems of animal agriculture.
Animal behavior, animal welfare, conservation behavior; behavioral assays of animal welfare, environmental enrichment for zoo and aquarium animals; zoo animal behavior and its impact on zoo-goers.
Meat safety; meat quality; shelf-life of meat and meat products; post-harvest food-borne pathogen control; characterizing pathogen and whole microbial community profiles present in meat production chain; effect of feeding system on degree of antimicrobial resistance and pathogen prevalence in livestock and poultry.
Research in immunogenetics, molecular genetics, functional genomics, and bioinformatics in poultry. Focused on elucidating the molecular and cellular mechanisms of host-pathogen interaction including disease resistance, immune response, and pathogenesis of infection. The overall goals are to understand genetic regulation of host response and basic mechanisms of pathogen virulence in animals, to identify host and pathogen genes that are involved in the host-pathogen interplay. The pathogens of interest are food-borne bacteria such as Campylobacter and Salmonella and avian influenza virus.
Ruminant nutrition; feedlot cattle nutrition and management; factors associated with digestive function.